Editorial: Genetics and epigenetics of fetal alcohol spectrum disorders

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Editorial: Genetics and epigenetics of fetal alcohol spectrum disorders

Citation: Mason S and Zhou FC (2015) Editorial: Genetics and epigenetics of fetal alcohol spectrum disorders. Children born to mothers who drink during pregnancy are at risk for growth retardation, memory, learning, and cognitive deficits under a lifelong disability known as Fetal Alcohol Spectrum Disorders (FASD), which occurs at a high rate in the US (∼1/100 live births) and worldwide. There ...

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Focus On: Epigenetics and Fetal Alcohol Spectrum Disorders

Epigenetic changes-stable but potentially reversible alterations in a cell's genetic information that result in changes in gene expression but do not involve changes in the underlying DNA sequence-may mediate some of the detrimental effects of prenatal alcohol exposure and contribute to the deficits and abnormalities associated with fetal alcohol spectrum disorders. These epigenetic processes a...

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Fetal Alcohol Spectrum Disorders.

Prenatal exposure to alcohol can damage the developing fetus and is the leading preventable cause of birth defects and intellectual and neurodevelopmental disabilities. In 1973, fetal alcohol syndrome was first described as a specific cluster of birth defects resulting from alcohol exposure in utero. Subsequently, research unequivocally revealed that prenatal alcohol exposure causes a broad ran...

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Fetal Alcohol Spectrum Disorders

Forty years ago, alcohol was not commonly recognized as a teratogen, an agent that can disrupt the development of a fetus. Today, we understand that prenatal alcohol exposure induces a variety of adverse effects on physical, neurological, and behavioral development. Research supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) has contributed to the identification of the ...

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Fetal alCoHol sPeCtruM disorders

Objective: To conduct a combined analysis of the estimated effects of maternal average weekly alcohol consumption, and any binge drinking, in early to mid pregnancy on general intelligence, attention, and executive function in 5-year-old children. Design: Follow-up study. Setting: Neuropsychological testing in four Danish cities 2003–2008. Population: A cohort of 1628 women and their children s...

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ژورنال

عنوان ژورنال: Frontiers in Genetics

سال: 2015

ISSN: 1664-8021

DOI: 10.3389/fgene.2015.00146